Killer Nerve Disease?

Guillain-Barré Syndrome (GBS): Killer Nerve Disease Risk with Swine Flu Vaccine Discussed Among UK Experts

Guillain-Barré Syndrome (GBS): Killer Nerve Disease Risk with Swine Flu Vaccine Discussed Among UK Experts

Saturday August 15 2009 11:35 pm Tags: Swine Flu, vaccination, vaccine ShareThis (E-Mail, Facebook, Twitter & More)

A confidential letter sent by the United Kingdom Health Protection Agency to about 600 senior neurologists on July 29, 2009 warns that the latest Swine Flu Vaccination is linked to the deadly nerve disease Guillain-Barre Syndrome (GBS).

The letter advises doctors that they must be alert for an increase in Guillain-Barre Syndrome (GBS), an autoimmune disease that involves an acute inflammatory demyelenating polyneuropathy (AIDP) of the peripheral nervous system. The disease is frequently severe with an ascending paralysis starting with weakness in the legs, then affects the arms, face and deep tendon reflexes. Frequently, the lower cranial nerves may be affected, leading to bulbar weakness, (oropharyngeal dysphagia, that is difficulty with swallowing, drooling, and/or maintaining an open airway) and respiratory difficulties.

Prompt treatment by removing blood and plasma, separating blood cells from the plasma, treating the plasma by removing disease-causing antibodies, and then returning plasma and blood cells to the patient. In some cases, the plasma is returned from a donor (plasma exchange). The treatment is accompanied by medical and immunosuppressive therapy for long term management to prevent target host nerve tissue from being attacked by antibodies.

The disease process is initiated by foreign antigens from an infectious disease, contaminated vaccine, or possibly the vaccine itself. GBS is a form of autoimmune disorder with a delayed hypersensitivity reaction, or a rare manifestation of serum sickness, or transient syndrome resembling serum sickness with loss of appetite, nausea, vomiting, and stomach pain accompanied by weakness (tired feeling), chills, and low grade fever. There is also possible evidence of brain involvement, indicated by lethargy and migraine headaches, although one theory of the cause of migraine is a central nervous system (CNS) disorder, or Bickerstaff’s brain stem encephalitis, a regional variant of GBS.

Typical pain is occipital or in the back of the head. Alterations of consciousness accompany this headache type. The brainstem is affected and implicated in the maintenance of arousal, but is a worrisome feature with this type of headache, which is called a Bickerstaff migraine. Altered brainstem functions result in clumsiness and gait unsteadiness, such as “pulling to the right” and are associated with Bickerstaff migraine, a variant of GBS.

Usually recovery starts after 4th week from the onset of the disorder. Approximately 80% of patients have a complete recovery within a few months to a year, although minor findings may persist, such as areflexia. About 5–10% recover with severe disability, with most of such cases involving severe proximal motor and sensory axonal nerve damage with inability of axonal regeneration.

The United Kingdom Health Protection Agency letter to neurologists refers to a vaccine in the United States in 1976 when more people died (25) from GBS respiratory paralysis than from the flu itself, when about 500 cases of GBS were diagnosed, when symptoms appeared within days of the vaccination, when the vaccine was thought to increase the risk of GBS up to eight times, and when the vaccine was withdrawn in ten weeks after the connection of the vaccine to GBS was recognized.

Related links …

Swine Flu Vaccine Linked to Deadly Nerve Disease

Merck Manual
Guillain-Barré Syndrome (GBS) – (Acute Idiopathic Polyneuritis; Acute Inflammatory Demyelinating Polyradiculoneuropathy)

Guillain-Barré Syndrome

Guillain Barre Syndrome

The most severe and obvious complication of Serum sickness is Guillain Barre Syndrome. Serum sickness is a type III hypersensitivity reaction that results from the injection of heterologous or foreign protein or serum.  The most serious complications of serum sickness are nerve conditions such as Guillain-Barre syndrome and peripheral neuritis.

Serum sickness is a reaction to an antiserum derived from an animal source. It is a type of hypersensitivity, specifically immune complex (type 3) hypersensitivity. Serum sickness typically develops up to ten days after exposure to the antiserum, and symptoms are similar to an allergic reaction. However, it is different from anaphylaxis, since the symptoms are not instantaneous (onset is typically 2-4 weeks after exposure).

Serum Sickness

StateMaster – Encyclopedia: Serum sickness

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One Response to Killer Nerve Disease?

  1. Pingback: pandemic & human guinea pigs ? « Medicaries Blog

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